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	Provedor de dados OAK (2) BJMBR (2) BJID (1) J. Venom. Anim. Toxins incl. Trop. Dis. (1) Autor Afonso,L.C.C. (1) Barral,A. (1) Barral-Netto,M. (1) Brodskyn,C. (1) Carvalho,E.M. (1) Chu,Ming (1) Hashiguchi-Kato, Rie (1) MG,Morsi (1) MM,Elgharabawy (1) Makala, Levi H. C. (1) Matsuki, Naoaki (1) NA,Hamed (1) Nagasawa, Hideyuki (1) Neumann,E. (1) Nicoli,J.R. (1) Ohmori, Takashi (1) Ono, Kenichiro (1) RA,Harfoush (1) RAA,Nour el deen (1) Ramos,M.G. (1) Mais... Palavra-chave IL-12 (6) Cytokines (2) IFN-γ (2) Acute myeloid leukemia (1) Babesia rodhaini (1) Cellular immunity (1) Cervical cancer (1) Dendritic cells (1) ELISA (1) HBsAg (1) HCV (1) Host resistance (1) Human leishmaniasis (1) Human papillomavirus type 16 (1) IL-10 (1) IL-13 (1) Immunoregulation (1) Lactobacillus (1) Macrophages (1) Mouse (1) Mais... Tipo do documento Info:eu-repo/semantics/article (4) Ano 2014 (1) 2011 (1) 2009 (1) 2004 (1) 2003 (1) 1998 (1) Mais... País Brazil (4) Japan (2) Idioma Inglês (6)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 6 Primeira ... 1 ... Última DENDRITIC CELLS AND HOST RESISTANCE TO TOXOPLASMA GONDII OAK Makala, Levi H. C.; Nagasawa, Hideyuki. Palavras-chave: Toxoplasma gondii; IL-12; IFN-γ; Dendritic cells; Host resistance; Mouse. Ano: 2003 URL: http://ir.obihiro.ac.jp/dspace/handle/10322/634 Human_Leishmaniasis@cytokines.bahia.br BJMBR Barral-Netto,M.; Brodskyn,C.; Carvalho,E.M.; Barral,A.. The cell-mediated immune response is critical in the resistance to and recovery from leishmaniasis. Cytokines are central elements in mounting an immune response and have received a great deal of attention in both human and experimental leishmaniasis. IFN-<FONT FACE="Symbol">g</font> is responsible for macrophage activation leading to leishmanicidal mechanisms. Understanding the balance of cytokines that lead to enhanced production of or synergize with IFN-<FONT FACE="Symbol">g</font>, and those cytokines that counterbalance its effects is fundamental for developing rational immunotherapeutic or immunoprophylactic approaches to leishmaniasis. Here we focus on the cytokine balance in human leishmaniasis, particularly IL-10 as an... Tipo: Info:eu-repo/semantics/article Palavras-chave: Cytokines; Human leishmaniasis; Immunoregulation; IL-12; IL-10. Ano: 1998 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1998000100021 Interleukin-12 gene adjuvant increases the immunogenicity of virus-like particles of human papillomavirus type 16 regional variant strain BJID Wei,Lanlan; Chu,Ming; Zhang,Qingmeng; Wang,Yan; Shang,Qinglong; Zhang,Yunyan; Zhang,Guangmei. Objectives:To analyze the immunogenicity of virus-like particles (VLP) of human papillomavirus type 16 (HPV16) isolated in East China and the adjuvant potential of interleukin-12 (IL-12).Methods:The variant HPV16 L1VLP expressed in sf9 insect cells were purified with cesium chloride gradient centrifugation. BALB/c mice were vaccinated with VLP (L1N), VLP with Freund's adjuvant (L1A) or VLP with IL-12 recombinant plasmid (L1P). HPV16 VLP specific IgG and IFN-γ level in the serum were detected by ELISA, and the percentage of CD4+ and CD8+ in spleen cells was detected with flow cytometry.Results:The titers of serum IgG antibodies in vaccinated groups were higher than in negative control and the serum antibodies mainly recognized conformation-dependent HPV16... Tipo: Info:eu-repo/semantics/article Palavras-chave: Cervical cancer; Human papillomavirus type 16; Virus-like particle; Cellular immunity; IL-12. Ano: 2014 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702014000100065 Lactobacillus delbrueckii UFV-H2b20 induces type 1 cytokine production by mouse cells in vitro and in vivo BJMBR Neumann,E.; Ramos,M.G.; Santos,L.M.; Rodrigues,A.C.P.; Vieira,E.C.; Afonso,L.C.C.; Nicoli,J.R.; Vieira,L.Q.. Lactobacillus delbrueckii UFV-H2b20 has been shown to increase clearance of bacteria injected into the blood of germ-free mice. Moreover, it induces the production of type 1 cytokines by human peripheral mononuclear cells. The objective of the present study was to investigate the production of inflammatory cytokines [interleukin-12 (IL-12 p40), tumor necrosis factor-α (TNF-α), and interferon-γ (IFN-γ)] triggered in vitro by live, heat-killed or lysozyme-treated L. delbrueckii UFV-H2b20 and in vivo by a live preparation. Germ-free, L. delbrueckii-monoassociated and lipopolysaccharide (LPS)-resistant C3H/HeJ mice were used as experimental models. UFV-H2b20 induced the production of IL-12 p40 and TNF-α by peritoneal cells and IFN-γ by spleen cells from... Tipo: Info:eu-repo/semantics/article Palavras-chave: Probiotics; Cytokines; Macrophages; IFN-γ; IL-12; Lactobacillus. Ano: 2009 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2009000400008 Levels of interleukins 12 (IL-12) and 13 (IL-13), hepatitis B and C serology, and blood cultures among acute myeloid leukemia (AML) patients in Egypt J. Venom. Anim. Toxins incl. Trop. Dis. RAA,Nour el deen; RA,Harfoush; MM,Elgharabawy; NA,Hamed; MG,Morsi. There is an interest in the use of IL-12 as a possible anti-cancer drug to induce immune responses and anti-IL-13 formulations to treat the undesirable effects of IL-13. Thus, the present study aimed at analyzing IL-12 and IL-13 profiles, viral hepatitis serology and blood cultures in acute myeloid leukemia (AML) patients. Forty individuals (20 without septicemia - Group A, and 20 with septicemia - Group B) and 20 healthy controls were evaluated. Hepatitis B virus antigens (HBsAg) and hepatitis C virus antibodies (HCV Ab) were quantified using commercial ELISA kits. IL-12 and IL-13 levels were estimated in culture supernatant of mitogen-stimulated peripheral blood mononuclear cells by ELISA. Significantly low IL-12 values were observed among AML patients... Tipo: Info:eu-repo/semantics/article Palavras-chave: Acute myeloid leukemia; IL-12; IL-13; HBsAg; HCV; ELISA. Ano: 2011 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992011000300009 SERUM INTERLEUKIN-12 LEVELS AND SPLENIC HELPER T CELL SUBPOPULATION IN BABESIA RODHAINI INOCULATED MICE PREIMMUNIZED WITH BABESIA MICROTI OAK Hashiguchi-Kato, Rie; Thi, Pham Ngoc; Ohmori, Takashi; Tamahara, Satoshi; Tomihari, Mizuki; Shimada, Terumasa; Matsuki, Naoaki; Ono, Kenichiro. Palavras-chave: Serum; IL-12; Babesia rodhaini; Preimmunized mice. Ano: 2004 URL: http://ir.obihiro.ac.jp/dspace/handle/10322/644 Registros recuperados: 6 Primeira ... 1 ... Última

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